- Course Introduction
- 01: Evidence & DNA
- 02: Forensic Biology
- 03: DNA Extraction & Quantitation
- 04: DNA Amplification
- 05: Amplified DNA Product Separation
- 06: STR Data Analysis & Interpretation
- 07: Population Genetics & Statistics
- 08: Communicating Results
- 09: Other DNA Markers & Technologies
- Course Resources
- Laboratory Training Manual
President's DNA Initiative
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Advancing Justice Through DNA Technology
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Advancing Justice Through DNA Technology
DNA Analyst Training
DQ-Alpha
Home > Evidence & DNA > DNA > DNA Typing by RFLP Analysis > DQ-Alpha
DQ-Alpha has four main alleles, numbered 1 through 4. The DQ-Alpha 1 and 4 alleles have sub-types (1.1, 1.2, 1.3 and 4.1, 4.2, 4.3). However, the strips could not recognize the specific 1.2 allele nor could they distinguish between the 4.2 and 4.3 alleles.
The concept was extended to incorporate a number of other loci to be typed concomitantly with DQ-Alpha, and marketed as Polymarker in 1993. A kit containing reagent for both DQ-Alpha and Polymarker became quite popular. The system was sensitive and easy to use but even the combination kit did not afford the discrimination power of RFLP.
