- Course Introduction
- 01: Evidence & DNA
- 02: Forensic Biology
- 03: DNA Extraction & Quantitation
- 04: DNA Amplification
- Overview
- Introduction
- Amplification
- Primer Design
- Primer Length
- Primer Melting Temperature
- Primer Annealing Temperature
- Values for Tm
- Maximum 3′ Stability
- GC Content Percentage
- No Secondary Structures
- No Self-complementarity
- No Complementarity To Other Primers
- No Long Runs With The Same Base
- Distance Between Two Primers On Target Sequence
- Plateau Effect
- Thermal Cyclers
- Thermal Cycling Parameter and Optimization
- Works Cited & Online Links
- Locus Selection
- Multiplexing
- Contamination
- Overview
- 05: Amplified DNA Product Separation
- 06: STR Data Analysis & Interpretation
- 07: Population Genetics & Statistics
- 08: Communicating Results
- 09: Other DNA Markers & Technologies
- Course Resources
- Laboratory Training Manual
President's DNA Initiative
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Advancing Justice Through DNA Technology
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Advancing Justice Through DNA Technology
DNA Analyst Training
Y-STRs
Home > DNA Amplification > Locus Selection > Other STR Loci > Y-STRs
In the United States, the development of Y-STR core loci has followed a pattern similar to the development of the CODIS core STR loci. The Scientific Working Group for DNA Analysis Methods (SWGDAM) created a subcommittee to investigate Y-STRs. The subcommittee reviewed published data and ran several hundred population database samples to evaluate various loci.
The subcommittee established the following 11 loci as the core Y-STR loci:
- DYS19
- DYS385 A/B
- DYS389I
- DYS389II
- DYS390
- DYS391
- DYS392
- DYS393
- DYS438
- DYS439
- DYS1908
With the establishment of the core loci, manufacturers have the specifications needed for the development of Y-STR kits
European laboratories have also established core Y-STR loci for forensic testing. ENFSI decided to use the same loci as the United States, minus DYS438 and DYS439.09