- Course Introduction
- 01: Evidence & DNA
- 02: Forensic Biology
- 03: DNA Extraction & Quantitation
- 04: DNA Amplification
- 05: Amplified DNA Product Separation
- 06: STR Data Analysis & Interpretation
- Data Troubleshooting
- Data Interpretation & Allele Calls
President's DNA Initiative
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Advancing Justice Through DNA Technology
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Advancing Justice Through DNA Technology
DNA Analyst Training
Mutations
Home > STR Data Analysis & Interpretation > Data Troubleshooting > Mutations
A mutation occurs when DNA is damaged or changed anywhere along the DNA strand. Mutations that occur in primer binding site regions or along the STR region can complicate interpretation.
The following are types of mutations that can occur:
Types of Mutations |
|
Mutation |
Description |
Insertion |
A base is inserted or added to the original DNA strand |
Deletion |
A base is deleted or removed from the original DNA strand |
Transition |
A transition between purine or pyrimidine bases occur in the original DNA strand
Transitions are more common than transversions |
Transversion |
A transversion between purine and pyrimidine bases occur in the original DNA strand
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