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Substrate Controls

Home > STR Data Analysis & Interpretation > Data Interpretation and Allele Calls > Step 1: Internal Size Standards and Allelic Ladders > Substrate Controls
photo of a substrate control being cut from near a blood stain

Some laboratories may include substrate controls in the process. These controls aid in troubleshooting inhibition arising from the substrate. In addition, substrate controls may show background DNA associated with the source of the biological stain being tested, and therefore assist in mixture interpretation. Evaluation and interpretation of data obtained from substrate controls is assessed on a case-by-case basis.

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