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Microchip Capillary Electrophoresis

Home > Other DNA Markers & Technologies > Techniques > Miniaturization Techniques > Microchip Capillary Electrophoresis
Microchip capillary electrophoresis

Microchip capillary electrophoresis is a microfluidic technology that applies semiconductor-like microfabrication techniques to connect interacting fluid reservoirs.  Instead of using valves and pumps, the necessary reagents and hybridization steps are accomplished through timing and exposure, versus turning off and on of valves. 

Examples of Microchip Technology

  • High-speed capillary electrophoresis (CE) chip separation was completed in two minutes for a salmonella DNA assay.01
  • Studies report that capillary array electrophoresis (CAE) microplates, comprised of micromachined glass wafers, can analyze 96 samples in less than 8 minutes.02 
  • A portable genetic analysis microsystem performs rapid detection of pathogens. This system contains microfabricated heaters and temperature sensors with fluorescence detection optics.03

CE microchip technology, compared to the conventional CE analysis, requires a minimal use of reagents.  This has the potential to significantly reduce analysis costs.

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